招贤纳士

人才理念

多元包容 团队精神 帮助成长


团队建设

工作机会

关键词
职位类别
  • 岗位名称
  • 需求专业
  • 工作地点
  • 人数
  • 发布时间
  • Scientist/Senior Scientist in Cheminformatics / Data Scientist
  • cheminformatics / bioinformatics / computer science / statistics or closely related discipline
  • 深圳/佛山
  • 若干
  • 2021-08-31
  • >

Role and Responsibilities:

1. Serve as a data scientific expert using advanced web-based technology to drive the discovery of new medicines.

2. Develop web application to perform computational chemistry/biology calculations and result analysis

3. Develop web-based visualization tools to analyze the bioactivity/ADMET data, QSAR

4. Collect, process, analyze and model chemical/biological data via database technology and application.

5. Assist on the development of cheminformatics/bioinformatics tools and machine learning model with the CADD team

6. Work closely with CADD/Medicinal chemistry teams.


Preferred qualifications:

1. Bachelor or above degree in cheminformatics / bioinformatics / computer science / statistics or closely related discipline.

2. Strong coding skills in at least one scientific programming language (Python, R, C++, etc).

3. Expertise in web UI design/Data visualization and web coding skills (HTML/CSS, PHP, JavaScript, front frame).

4. Familiar with database technology (MYSQL/MariaDB/PostgreSQL).

5. Experience with cheminformatics tools (Rdkit/Openbabel /CDK /Biopython et al.) is a plus.

6. Experience with machine learning/deep learning (sklearn, pytorch, tensorflow) is a plus.

7. Experience with molecular modeling (MD, QM, docking, virtual screening et al.) and CADD tools (MOE, Schrodinger, Knime, JChem, Spotfire, Plexus Connect) is a plus.


申请该职位
  • 有机合成高级研究员(Senior Scientist)
  • 有机化学或药物化学
  • 佛山
  • 若干
  • 2021-07-01
  • >

岗位职责:

1. 在上级领导的指导下,参与小分子研发项目的全部过程,包括药物先导化合物和候选化合物的设计、合成及测试等;

2. 能够熟练进行各种文献的查阅和图谱解析,包括一维和二维核磁谱图解析;

3. 能够熟练地完成多种化学反应,独立设计和进行多步有机合成合成反应;

4. 全面了解化学实验安全操作方法,能够预见可能发生的安全问题;

5. 维护实验室安全及日常运行;

6. 诚实、正直,具有优秀的团队合作精神,宣扬原力的核心价值和文化.


任职要求:

1. 有机化学或药物化学相关专业,博士学历,或硕士毕业5年及以上相关行业工作经验,

2. 精通各类有机合成反应,

3. 具有熟练的英语阅读和书写能力。

申请该职位
  • 药化项目负责人
  • PhD in Organic or Medicinal Chemistry
  • 佛山
  • 1人
  • 2021-07-01
  • >

Responsibilities:

Drive small molecule medicinal chemistry program on:

Molecular design and SAR evaluation

Implementation of organic syntheses and problem solving

Directing a team of internal and external (CRO) chemists to execute chemistry plan

Preparation of experimental for report and patent filing

Interacting cross-functionally to collect vital data

Presenting resulting and data in program meeting and to review committee

Serve as chemistry leader on:

Participating on cross-functional project teams to evaluate, prioritize and set strategy to positively influence project direction and timelines

Build strong working relationship with internal and external colleagues and organizations

Training, building and growing the chemistry team, and ensuring maximal productivity

Acting as a resource and mentor to team members

Managing external (CRO) FTE

Sourcing of reagent and its procurement cost effectively

Drive quality and speed to meet departmental and company goals

Grow to become an influential drug hunter and scientist


Qualifications:

1. PhD in Organic or Medicinal Chemistry

2. At least 3 years industry experience in small molecule medicinal chemistry

3. Excellent communication skill

4. Sufficient language proficiency to present in English

申请该职位
  • 体内药效研究员
  • 医学、药学或生物学
  • 佛山
  • 若干
  • 2021-07-01
  • >

岗位职责:

1、负责多种动物细胞培养,包括传代,换液,冻存,复苏,细胞计数等。

2、负责建立小鼠肿瘤疾病动物模型,包括原位移植、皮下成瘤、小鼠异种移植动物模型等。

3、负责实验数据的分析和统计。

4、完成领导交代的其他工作任务。


岗位要求:

1、医学、药学或生物学相关专业

2、本科及以上学历

3、责任心强,有意愿从事细胞培养和动物实验。

4、有小分子动物实验经验尤佳

申请该职位
  • 体外药效研究员
  • 细胞生物学、免疫学、分子生物学、药理学
  • 佛山
  • 若干
  • 2021-07-01
  • >

岗位职责:

1.  负责项目体外化合物筛选,包括筛选方案的设计和优化,完成,包括但不限于各类酶活性、蛋白亲和力测试。

2. 能独立完成体外药理学相关实验方案的设计、实施和结果分析,及时解决实验进程中产生的问题。

3. 在深刻理解靶点生物学功能的基础上,探索抗肿瘤或免疫调节相关药物的作用机制。

4. 负责撰写相关的实验记录及研究报告。

5. 参与实验室的管理、培训及安全维护。


岗位要求:

1、 硕士以上学历,细胞生物学、免疫学、分子生物学、药理学等相关专业。

2、具有抗肿瘤药物研发经验或相关研究背景;熟悉新药研发流程,在新药研发公司具2年以上工作经验者优先。

3、具备较强的细胞及分子生物学实验技能,熟练掌握细胞培养、流式细胞术、ELISA、WB等常规实验方法和技术。

4、具备较强的数据分析、问题解决能力,熟练掌握GraphPad Prism、FlowJo等专业分析软件。

5、较强的沟通表达能力,善于团队协作,具有一定的分析解决问题的能力。

6、工作主动,责任心强,工作效率高,能独立完成负责的实验项目。

申请该职位
  • 体外药效资深研究员
  • Drug discovery experience are preferred
  • 佛山
  • 1人
  • 2021-07-01
  • >

Responsibility:

1.a member of Quantitative Biology team, the incumbent will partner with discovery functional teams to support oncology drug discovery by in vitro efficacy evaluation of small molecule drug candidates via high-throughput biochemical and/or biophysical screening as well as in-dept mechanism of action (MOA) investigation.

2.span>

3.Develop biochemical and/or biophysical assays on novel drug targets, and execute assay evaluation, optimization and troubleshooting.

4.Design, execute and optimize in vitro screening/testing workflow, and perform assay data and visualization, and present assay results and lead recommendations.

5.Plan and document results of routine assays and manage electronic assay reports.

6.Manage lab safety and operation.


Required qualifications:

1.MS (3 years + experience) or Ph.D in enzymology, biochemistry, biophysics, cell biology, molecular biology, immunology or related biological disciplines.

2.Fluency in data analysis, visualization and experience in kinetic data analysis software (GraphPad, KaleidoGraph, Origin etc).

3.Strong communication and presentation skills.

Preferred qualifications

1.Demonstrated qualifications in enzyme assay development, structure & activity relationship (SAR). Drug discovery experience are preferred.

2.Knowledge and Experience in enzyme inhibitor modality, mechanism and kinetics.

申请该职位